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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733199
Species: Mus musculus
RGD Object: Gene
Symbol: Top1
Name: topoisomerase (DNA) I
Acc ID: CHEBI:82388
Term: p-anisidine
Definition: A substituted aniline that is aniline in which the hydrogen para to the amino group has been replaced by a methoxy group. It is used as a reagent for the detection of oxidation products such as aldehydes and ketones in fats and oils.
Chemical ID: MESH:C013813
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Top1decreases expressionEXP 6480464CTD4-anisidine results in decreased expression of TOP1 mRNAPMID:12929121
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