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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732528
Species: Mus musculus
RGD Object: Gene
Symbol: Nat2
Name: N-acetyltransferase 2 (arylamine N-acetyltransferase)
Acc ID: CHEBI:82337
Term: 2-Amino-3-methyl-9H-pyrido[2,3-b]indole
Definition: A pyridoindole that has formula C12H11N3.
Chemical ID: MESH:C017821
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nat2increases activityISONAT2 (Homo sapiens)6480464CTDNAT2 protein results in increased activity of 2-amino-3-methyl-9H-pyrido(2,3-b)indolePMID:14729582
Nat2multiple interactionsISONAT2 (Homo sapiens)6480464CTDNAT2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-3-methyl-9H-pyrido(2,3-b)indolePMID:28160022
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