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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10436
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:82284
Term: 2-Amino-9H-pyrido[2,3-b]indole
Definition: A pyridoindole that has formula C11H9N3.
Chemical ID: MESH:C017822
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1increases expressionISOCYP1A1 (Homo sapiens)6480464CTD2-amino-9H-pyrido(2,3-b)indole results in increased expression of CYP1A1 mRNAPMID:27644595
Cyp1a1multiple interactionsISOCyp1a1 (Rattus norvegicus)6480464CTDCYP1A1 protein results in increased metabolism of and results in increased activity of 2-amino-9H-pyrido(2,3-b)indolePMID:1913651
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