GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pcsk9 | increases expression | EXP | | 6480464 | CTD | pioglitazone results in increased expression of PCSK9 protein | PMID:22593575 | Pcsk9 | multiple interactions | EXP | | 6480464 | CTD | [pioglitazone co-treated with U 0126] results in increased secretion of PCSK9 protein | PMID:22593575 | Pcsk9 | increases expression | ISO | PCSK9 (Homo sapiens) | 6480464 | CTD | pioglitazone results in increased expression of PCSK9 mRNA; pioglitazone results in increased expression of PCSK9 protein | PMID:22593575 | Pcsk9 | multiple interactions | ISO | PCSK9 (Homo sapiens) | 6480464 | CTD | pioglitazone promotes the reaction [PPARG protein results in increased expression of PCSK9 mRNA] | PMID:22593575 | |
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