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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308277
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr1b10
Name: aldo-keto reductase family 1 member B10
Acc ID: CHEBI:82195
Term: Clofop
Definition: An aromatic ether that has formula C15H13ClO4.
Chemical ID: MESH:C006012
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1b10decreases activityISOAKR1B10 (Homo sapiens)6480464CTDfenofibric acid results in decreased activity of AKR1B10 protein; fenofibric acid results in decreased activity of AKR1B10 protein mutant formPMID:18325492
Akr1b10multiple interactionsISOAKR1B10 (Homo sapiens)6480464CTDfenofibric acid inhibits the reaction [AKR1B10 protein results in increased reduction of Daunorubicin]; fenofibric acid inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]PMID:19028477
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