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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2126
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apex1
Name: apurinic/apyrimidinic endodeoxyribonuclease 1
Acc ID: CHEBI:8207
Term: (+)-pilocarpine
Definition: The (+)-enantiomer of pilocarpine.
Chemical ID: MESH:D010862
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apex1affects localizationEXP 6480464CTDPilocarpine affects the localization of APEX1 mRNAPMID:20206232
Apex1decreases expressionEXP 6480464CTDPilocarpine results in decreased expression of APEX1 proteinPMID:20446108
Apex1increases expressionEXP 6480464CTDPilocarpine results in increased expression of APEX1 mRNAPMID:17971868
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