GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases activity | EXP | | 6480464 | CTD | Pilocarpine results in increased activity of CASP3 protein | PMID:19631748 | Casp3 | increases cleavage | EXP | | 6480464 | CTD | Pilocarpine results in increased cleavage of CASP3 protein | PMID:18815271 | Casp3 | increases expression | EXP | | 6480464 | CTD | Pilocarpine results in increased expression of CASP3 protein modified form | PMID:18708038 | Casp3 | multiple interactions | EXP | | 6480464 | CTD | ZFP110 protein mutant form inhibits the reaction [Pilocarpine results in increased cleavage of CASP3 protein] | PMID:18815271 | Casp3 | increases activity | ISO | Casp3 (Rattus norvegicus) | 6480464 | CTD | Pilocarpine results in increased activity of CASP3 protein | PMID:21062633 | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Pilocarpine results in increased activity of CASP3 protein | PMID:19927300 | Casp3 | increases cleavage | ISO | Casp3 (Rattus norvegicus) | 6480464 | CTD | Pilocarpine results in increased cleavage of CASP3 protein | PMID:19429016 PMID:22824136 | Casp3 | multiple interactions | ISO | Casp3 (Rattus norvegicus) | 6480464 | CTD | [Pilocarpine co-treated with Lithium] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [Pilocarpine results in increased cleavage of CASP3 protein]; Dizocilpine Maleate inhibits the reaction [Pilocarpine results in increased cleavage of CASP3 protein]; Pilocarpine results in increased cleavage of and results in increased activity of CASP3 protein; Tacrolimus inhibits the reaction [[Lithium co-treated with Pilocarpine] results in increased activity of CASP3 protein]; Thioctic Acid inhibits the reaction [Pilocarpine results in increased activity of CASP3 protein] | PMID:12097334 PMID:20149694 PMID:21062633 PMID:22824136 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Pilocarpine results in increased activity of CASP3 protein]; 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Pilocarpine results in increased activity of CASP3 protein]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Pilocarpine results in increased activity of CASP3 protein]; Verapamil inhibits the reaction [Pilocarpine results in increased activity of CASP3 protein] | PMID:19927300 | | ||||||||||||||||||||||
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