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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69218
Species: Mus musculus
RGD Object: Gene
Symbol: Aldh2
Name: aldehyde dehydrogenase 2, mitochondrial
Acc ID: CHEBI:81786
Term: Oxadiazon
Definition: An aromatic ether that has formula C15H18Cl2N2O3.
Chemical ID: MESH:C012466
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:692206480464CTDoxadiazon results in decreased expression of ALDH2 mRNA

PMID:30391265
multiple interactionsISORGD:692206480464CTDoxadiazon results in decreased expression of and results in decreased activity of ALDH2 protein

PMID:30391265
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.