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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:81584
Term: 2,2',4,4'-Tetrabromodiphenyl ether
Definition: An organobromine compound that has formula C12H6Br4O.
Chemical ID: MESH:C511295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NQO1affects expressionEXP 6480464CTD2,2',4,4'-tetrabromodiphenyl ether affects the expression of NQO1 mRNAPMID:31173147
NQO1decreases expressionEXP 6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of NQO1 mRNAPMID:25659769
NQO1multiple interactionsEXP 6480464CTD[Eicosapentaenoic Acid analog co-treated with Docosahexaenoic Acids analog] inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of NQO1 mRNA]PMID:25659769
NQO1increases expressionISONqo1 (Rattus norvegicus)6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in increased expression of NQO1 mRNAPMID:32679240
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