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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734104
Species: Mus musculus
RGD Object: Gene
Symbol: Nr1h4
Name: nuclear receptor subfamily 1, group H, member 4
Acc ID: CHEBI:81584
Term: 2,2',4,4'-Tetrabromodiphenyl ether
Definition: An organobromine compound that has formula C12H6Br4O.
Chemical ID: MESH:C511295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1h4affects expressionEXP 6480464CTD2,2',4,4'-tetrabromodiphenyl ether affects the expression of NR1H4 mRNAPMID:30294300
Nr1h4increases activityEXP 6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in increased activity of NR1H4 proteinPMID:29112739
Nr1h4increases expressionISONR1H4 (Homo sapiens)6480464CTD2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of NR1H4 mRNAPMID:19095052
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