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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731889
Species: Homo sapiens
RGD Object: Gene
Symbol: CDK1
Name: cyclin dependent kinase 1
Acc ID: CHEBI:81584
Term: 2,2',4,4'-Tetrabromodiphenyl ether
Definition: An organobromine compound that has formula C12H6Br4O.
Chemical ID: MESH:C511295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDK1decreases expressionEXP 6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of CDK1 mRNAPMID:31173147
CDK1increases expressionEXP 6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CDK1 mRNA; 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CDK1 proteinPMID:26988655
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