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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70924
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdzk1
Name: PDZ domain containing 1
Acc ID: CHEBI:81584
Term: 2,2',4,4'-Tetrabromodiphenyl ether
Definition: An organobromine compound that has formula C12H6Br4O.
Chemical ID: MESH:C511295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdzk1increases expressionISOPDZK1 (Homo sapiens)6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in increased expression of PDZK1 mRNAPMID:30796839
Pdzk1multiple interactionsISOPDZK1 (Homo sapiens)6480464CTD[2,2',4,4'-tetrabromodiphenyl ether co-treated with hexabrominated diphenyl ether 153 co-treated with pentabrominated diphenyl ether 100] results in increased expression of PDZK1 mRNAPMID:30796839
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