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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62001
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Muc5ac
Name: mucin 5AC, oligomeric mucus/gel-forming
Acc ID: CHEBI:81584
Term: 2,2',4,4'-Tetrabromodiphenyl ether
Definition: An organobromine compound that has formula C12H6Br4O.
Chemical ID: MESH:C511295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Muc5acincreases expressionISOMUC5AC (Homo sapiens)6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in increased expression of MUC5AC mRNA; 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of MUC5AC proteinPMID:31622892
Muc5acmultiple interactionsISOMUC5AC (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of MUC5AC mRNA]; Acetylcysteine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of MUC5AC protein]PMID:31622892
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