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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313438
Species: Mus musculus
RGD Object: Gene
Symbol: Polr2e
Name: polymerase (RNA) II (DNA directed) polypeptide E
Acc ID: CHEBI:81584
Term: 2,2',4,4'-Tetrabromodiphenyl ether
Definition: An organobromine compound that has formula C12H6Br4O.
Chemical ID: MESH:C511295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Polr2eaffects expressionEXP 6480464CTD2,2',4,4'-tetrabromodiphenyl ether affects the expression of POLR2E mRNAPMID:30294300
Polr2edecreases expressionISOPOLR2E (Homo sapiens)6480464CTD2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of POLR2E proteinPMID:31675489
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