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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11476
Species: Mus musculus
RGD Object: Gene
Symbol: Ugt1a1
Name: UDP glucuronosyltransferase 1 family, polypeptide A1
Acc ID: CHEBI:81584
Term: 2,2',4,4'-Tetrabromodiphenyl ether
Definition: An organobromine compound that has formula C12H6Br4O.
Chemical ID: MESH:C511295
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTD2, 2', 4, 4'-tetrabromodiphenyl ether results in increased expression of UGT1A1 mRNA, 2, 2', 4, 4'-tetrabromodiphenyl ether results in increased expression of UGT1A7 mRNA

PMID:17964624
increases expressionISORGD:39356480464CTD2, 2', 4, 4'-tetrabromodiphenyl ether results in increased expression of UGT1A1 mRNA

PMID:20056577
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.