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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733190
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA4
Name: heat shock protein family A (Hsp70) member 4
Acc ID: CHEBI:81582
Term: 2,4-dibromophenyl 2,4,5-tribromophenyl ether
Definition: A polybromodiphenyl ether that is diphenyl ether in which the hydrogens at the 2, 4, 5, 2', and 4' positions have been replaced by bromines.
Chemical ID: MESH:C477694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA4decreases expressionISOHspa4 (Rattus norvegicus)6480464CTD2,2',4,4',5-brominated diphenyl ether results in decreased expression of HSPA4 proteinPMID:19954255
HSPA4increases expressionISOHspa4 (Rattus norvegicus)6480464CTD2,2',4,4',5-brominated diphenyl ether results in increased expression of HSPA4 proteinPMID:19954255
HSPA4increases expressionISOHspa4 (Mus musculus)6480464CTD2,2',4,4',5-brominated diphenyl ether results in increased expression of HSPA4 proteinPMID:18550172
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