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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731072
Species: Homo sapiens
RGD Object: Gene
Symbol: VEGFA
Name: vascular endothelial growth factor A
Acc ID: CHEBI:81555
Term: Enterolactone
Definition: A lignan that has formula C18H18O4.
Chemical ID: MESH:C029497
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
VEGFAmultiple interactionsEXP 6480464CTD2,3-bis(3'-hydroxybenzyl)butyrolactone inhibits the reaction [Estradiol results in increased secretion of VEGFA protein]; [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of VEGFA mRNAPMID:17289903 PMID:19167446
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