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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619871
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gclm
Name: glutamate cysteine ligase, modifier subunit
Acc ID: CHEBI:81543
Term: Tributyltin oxide
Definition: An inorganic molecular entity that has formula C24H54OSn2.
Chemical ID: MESH:C005961
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gclmdecreases expressionISOGCLM (Homo sapiens)6480464CTDbis(tri-n-butyltin)oxide results in decreased expression of GCLM mRNAPMID:26198647
Gclmincreases expressionISOGCLM (Homo sapiens)6480464CTDbis(tri-n-butyltin)oxide results in increased expression of GCLM mRNAPMID:21601586
Gclmincreases expressionISOGclm (Mus musculus)6480464CTDbis(tri-n-butyltin)oxide results in increased expression of GCLM mRNAPMID:21601586
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