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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3213
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ntrk2
Name: neurotrophic receptor tyrosine kinase 2
Acc ID: CHEBI:81526
Term: endrin
Definition: An organochlorine compound resulting from the epoxidation of the double bond of isodrin. It is the endo, endo stereoisomer of dieldrin. It is an insecticide mainly used on field crops such as cotton and grains and has also been used as a rodenticide to control mice and voles. The product is banned in many countries since it is a persistent organic pollutant.
Chemical ID: MESH:D004732
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ntrk2multiple interactionsISORGD:7313056480464CTD[Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK2 mRNA

PMID:28263720
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