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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621400
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1i3
Name: nuclear receptor subfamily 1, group I, member 3
Acc ID: CHEBI:81522
Term: 2,3,3',4,4',5-Hexachlorobiphenyl
Definition: A hexachlorobiphenyl that has formula C12H4Cl6.
Chemical ID: MESH:C087667
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i3increases activityISORGD:15526296480464CTD2 3 3' 4 4' 5-hexachlorobiphenyl results in increased activity of NR1I3 protein

PMID:19746742
Nr1i3multiple interactionsISORGD:15526296480464CTD2 3 3' 4 4' 5-hexachlorobiphenyl inhibits the reaction [Androstenols results in decreased activity of NR1I3 protein]

PMID:19746742
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