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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731081
Species: Homo sapiens
RGD Object: Gene
Symbol: PGR
Name: progesterone receptor
Acc ID: CHEBI:81520
Term: 2,3',4,4',5-Pentachlorobiphenyl
Definition: A pentachlorobiphenyl that has formula C12H5Cl5.
Chemical ID: MESH:C070055
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD2, 3', 4, 4', 5-pentachlorobiphenyl inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3, 20-dione results in increased activity of PGR protein]

PMID:26022396
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.