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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69106
Species: Mus musculus
RGD Object: Gene
Symbol: Nr1i2
Name: nuclear receptor subfamily 1, group I, member 2
Acc ID: CHEBI:81520
Term: 2,3',4,4',5-Pentachlorobiphenyl
Definition: A pentachlorobiphenyl that has formula C12H5Cl5.
Chemical ID: MESH:C070055
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i2increases activityISONR1I2 (Homo sapiens)6480464CTD2,3',4,4',5-pentachlorobiphenyl results in increased activity of NR1I2 proteinPMID:15885729 PMID:25680588
Nr1i2multiple interactionsISONR1I2 (Homo sapiens)6480464CTD2,3',4,4',5-pentachlorobiphenyl binds to and results in increased activity of NR1I2 proteinPMID:16054614
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