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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730870
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP1A1
Name: cytochrome P450 family 1 subfamily A member 1
Acc ID: CHEBI:81513
Term: 1,2,3,4,6,7,8-Heptachlorodibenzofuran
Definition: A dibenzofuran that has formula C12HCl7O.
Chemical ID: MESH:C473650
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP1A1increases expressionEXP 6480464CTD1,2,3,4,6,7,8-heptachlorodibenzofuran analog results in increased expression of CYP1A1 mRNA; 1,2,3,4,6,7,8-heptachlorodibenzofuran analog results in increased expression of CYP1A1 protein; 1,2,3,4,6,7,8-heptachlorodibenzofuran results in increased expression of CYP1A1 mRNA; 1,2,3,4,6,7,8-heptachlorodibenzofuran results in increased expression of CYP1A1 proteinPMID:25654323
CYP1A1increases expressionISOCyp1a1 (Rattus norvegicus)6480464CTD1,2,3,4,6,7,8-heptachlorodibenzofuran analog results in increased expression of CYP1A1 mRNA; 1,2,3,4,6,7,8-heptachlorodibenzofuran analog results in increased expression of CYP1A1 protein; 1,2,3,4,6,7,8-heptachlorodibenzofuran results in increased expression of CYP1A1 mRNA; 1,2,3,4,6,7,8-heptachlorodibenzofuran results in increased expression of CYP1A1 proteinPMID:25654323 PMID:29738842
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