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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2458
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:81507
Term: 1,2,3,7,8-Pentachlorodibenzofuran
Definition: A dibenzofuran that has formula C12H3Cl5O.
Chemical ID: MESH:C057584
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1increases expressionISOCyp1a1 (Mus musculus)6480464CTD1,2,3,7,8-pentachlorodibenzofuran results in increased expression of CYP1A1 mRNAPMID:24713691
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