GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sptlc2 | increases expression | EXP | | 6480464 | CTD | 2,3,7,8-tetrachlorodibenzofuran results in increased expression of SPTLC2 mRNA | PMID:34097992 | Sptlc2 | multiple interactions | EXP | | 6480464 | CTD | 2,3,7,8-tetrachlorodibenzofuran promotes the reaction [AHR protein binds to SPTLC2 promoter]; AHR gene mutant form inhibits the reaction [2,3,7,8-tetrachlorodibenzofuran results in increased expression of SPTLC2 mRNA] | PMID:34097992 | |
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