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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:81093
Term: kurarinol
Definition: A trihydroxyflavanone that is (2S)-flavanone substituted by hydroxy groups at positions 7, 2' and 4' , a methoxy group at position 5 and a (2S)-5-hydroxy-5-methyl-2-(prop-1-en-2-yl)hexyl group at position 8 respectively.
Chemical ID: MESH:C526229
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases activityISORGD:102896480464CTDkurarinol results in increased activity of CASP3 protein

PMID:24997323
Casp3increases activityISORGD:7310026480464CTDkurarinol results in increased activity of CASP3 protein

PMID:24997323
Casp3multiple interactionsISORGD:7310026480464CTDSTAT3 protein inhibits the reaction [kurarinol results in increased activity of CASP3 protein]

PMID:24997323
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