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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61996
Species: Rattus norvegicus
RGD Object: Gene
Symbol: F2
Name: coagulation factor II, thrombin
Acc ID: CHEBI:8107
Term: phenytoin
Definition: A imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5.
Chemical ID: MESH:D010672
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F2multiple interactionsISOF2 (Homo sapiens)6480464CTD[clobazam co-treated with Phenytoin] results in increased expression of [F2 protein binds to SERPINC1 protein]PMID:16376047
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