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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557024
Species: Mus musculus
RGD Object: Gene
Symbol: Gusb
Name: glucuronidase, beta
Acc ID: CHEBI:8107
Term: phenytoin
Definition: A imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5.
Chemical ID: MESH:D010672
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gusbdecreases activityEXP 6480464CTDPhenytoin results in decreased activity of GUSB proteinPMID:6696821
Gusbmultiple interactionsEXP 6480464CTDPhenytoin inhibits the reaction [Misonidazole results in increased activity of GUSB protein]PMID:6696821
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