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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737467
Species: Homo sapiens
RGD Object: Gene
Symbol: ADRB3
Name: adrenoceptor beta 3
Acc ID: CHEBI:8093
Term: phenylephrine
Definition: A member of the class of the class of phenylethanolamines that is (1R)-2-(methylamino)-1-phenylethan-1-ol carrying an additional hydroxy substituent at position 3 on the phenyl ring.
Chemical ID: MESH:D010656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ADRB3increases response to substanceEXP 6480464CTDADRB3 protein results in increased susceptibility to PhenylephrinePMID:16022967
ADRB3multiple interactionsEXP 6480464CTDamibegron inhibits the reaction [ADRB3 protein results in increased susceptibility to Phenylephrine]PMID:16022967
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