GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | EGR1 | increases expression | ISO | Egr1 (Rattus norvegicus) | 6480464 | CTD | Phenylephrine results in increased expression of EGR1; Phenylephrine results in increased expression of EGR1 mRNA | PMID:10779383 PMID:7905536 | EGR1 | multiple interactions | ISO | Egr1 (Mus musculus) | 6480464 | CTD | EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 mRNA]; EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 protein]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of SP1 mRNA] | PMID:10710348 PMID:15621046 | EGR1 | multiple interactions | ISO | Egr1 (Rattus norvegicus) | 6480464 | CTD | Phenylephrine promotes the reaction [EGR1 protein binds to FGF2 promoter] | PMID:10779383 | | ||||||||||||||||||||||
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