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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68374
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cox4i1
Name: cytochrome c oxidase subunit 4i1
Acc ID: CHEBI:8093
Term: phenylephrine
Definition: A member of the class of the class of phenylethanolamines that is (1R)-2-(methylamino)-1-phenylethan-1-ol carrying an additional hydroxy substituent at position 3 on the phenyl ring.
Chemical ID: MESH:D010656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cox4i1decreases expressionEXP 6480464CTDPhenylephrine results in decreased expression of COX4I1 proteinPMID:23818984
Cox4i1multiple interactionsEXP 6480464CTDCopper Sulfate inhibits the reaction [Phenylephrine results in decreased expression of COX4I1 protein]; periodate-oxidized adenosine inhibits the reaction [Phenylephrine results in decreased expression of COX4I1 protein]PMID:23818984
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