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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:8093
Term: phenylephrine
Definition: A member of the class of the class of phenylethanolamines that is (1R)-2-(methylamino)-1-phenylethan-1-ol carrying an additional hydroxy substituent at position 3 on the phenyl ring.
Chemical ID: MESH:D010656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxdecreases expressionEXP 6480464CTDPhenylephrine results in decreased expression of BAX proteinPMID:19910689
Baxmultiple interactionsEXP 6480464CTDPTHLH protein affects the reaction [Phenylephrine results in decreased expression of BAX protein]PMID:19910689
Baxincreases expressionISOBAX (Homo sapiens)6480464CTDPhenylephrine results in increased expression of BAX proteinPMID:31605733
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