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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344327
Species: Homo sapiens
RGD Object: Gene
Symbol: MYOCD
Name: myocardin
Acc ID: CHEBI:8093
Term: phenylephrine
Definition: A member of the class of the class of phenylethanolamines that is (1R)-2-(methylamino)-1-phenylethan-1-ol carrying an additional hydroxy substituent at position 3 on the phenyl ring.
Chemical ID: MESH:D010656
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MYOCDincreases expressionISOMyocd (Rattus norvegicus)6480464CTDPhenylephrine results in increased expression of MYOCD mRNA; Phenylephrine results in increased expression of MYOCD proteinPMID:16556869
MYOCDmultiple interactionsISOMyocd (Rattus norvegicus)6480464CTDMYOCD protein affects the reaction [Phenylephrine results in increased expression of ACTA2 mRNA]; MYOCD protein affects the reaction [Phenylephrine results in increased expression of NPPB mRNA]; MYOCD protein promotes the reaction [Phenylephrine results in increased expression of MYL2 protein]; MYOCD protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]; Phenylephrine promotes the reaction [MYOCD protein binds to NPPA promoter]PMID:14676212 PMID:16556869
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