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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:80845
Term: liquiritin
Definition: A flavanone glycoside that is liquiritigenin attached to a beta-D-glucopyranosyl residue at position 4' via a glycosidic linkage.
Chemical ID: MESH:C512196
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2multiple interactionsEXP 6480464CTDliquiritin inhibits the reaction [Monocrotaline results in decreased expression of NFE2L2 mRNA]PMID:29908794
Nfe2l2decreases response to substanceISORGD:7344326480464CTDNFE2L2 gene mutant form results in decreased susceptibility to liquiritinPMID:29908794
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