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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:80830
Term: Germacrone
Definition: A germacrane sesquiterpenoid that has formula C15H22O.
Chemical ID: MESH:C048393
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsISORGD:7310026480464CTD[germacrone results in increased susceptibility to Doxorubicin] which results in increased activity of CASP3 protein

PMID:29655913
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.