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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735541
Species: Homo sapiens
RGD Object: Gene
Symbol: BAD
Name: BCL2 associated agonist of cell death
Acc ID: CHEBI:80774
Term: tauroursodeoxycholic acid
Definition: A bile acid taurine conjugate derived from ursoodeoxycholic acid.
Chemical ID: MESH:C031655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BADmultiple interactionsEXP 6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ursodoxicoltaurine results in increased phosphorylation of and results in decreased activity of BAD protein]; ursodoxicoltaurine results in increased phosphorylation of and results in decreased activity of BAD proteinPMID:17559149
BADincreases phosphorylationISOBad (Rattus norvegicus)6480464CTDursodoxicoltaurine results in increased phosphorylation of BAD proteinPMID:12721362
BADmultiple interactionsISOBad (Rattus norvegicus)6480464CTDursodoxicoltaurine results in increased phosphorylation of and affects the localization of BAD protein; Wortmannin inhibits the reaction [ursodoxicoltaurine results in increased phosphorylation of and affects the localization of BAD protein]PMID:15190125
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