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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62396
Species: Mus musculus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:80774
Term: tauroursodeoxycholic acid
Definition: A bile acid taurine conjugate derived from ursoodeoxycholic acid.
Chemical ID: MESH:C031655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddit3multiple interactionsEXP 6480464CTDursodoxicoltaurine inhibits the reaction [2,4-dichlorophenol results in increased expression of DDIT3 mRNA]; ursodoxicoltaurine inhibits the reaction [[N-palmitoylsphingosine co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA]; ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of DDIT3 mRNA]; ursodoxicoltaurine inhibits the reaction [Gentamicins results in increased expression of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [N-palmitoylsphingosine results in increased expression of DDIT3 mRNA]PMID:27853103 PMID:28223344 PMID:29751043
Ddit3multiple interactionsISODdit3 (Rattus norvegicus)6480464CTDursodoxicoltaurine inhibits the reaction [Cisplatin results in increased expression of DDIT3 mRNA]; ursodoxicoltaurine inhibits the reaction [Cisplatin results in increased expression of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [Ethanol results in increased expression of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [Tunicamycin results in increased expression of DDIT3 protein]PMID:23544086 PMID:29027487 PMID:33631298
Ddit3multiple interactionsISODDIT3 (Homo sapiens)6480464CTDursodoxicoltaurine inhibits the reaction [Cyclosporine results in increased expression of and affects the localization of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [hydroquinone results in increased expression of and affects the localization of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [pachymic acid results in increased expression of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [Tunicamycin results in increased expression of DDIT3 protein]; ursodoxicoltaurine inhibits the reaction [Ursolic Acid results in increased expression of DDIT3 protein]PMID:24053669 PMID:24802810 PMID:29027487 PMID:35033536 PMID:35524978
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