GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tp53 | affects response to substance | EXP | | 6480464 | CTD | TP53 protein affects the susceptibility to ursodoxicoltaurine | PMID:17431217 | Tp53 | multiple interactions | EXP | | 6480464 | CTD | ursodoxicoltaurine inhibits the reaction [TP53 protein results in increased expression of BAX mRNA]; ursodoxicoltaurine results in increased expression of and results in increased stability of TP53 protein | PMID:15255934 PMID:17881359 | Tp53 | multiple interactions | ISO | TP53 (Homo sapiens) | 6480464 | CTD | ursodoxicoltaurine inhibits the reaction [[APP gene mutant form co-treated with PSEN1 gene mutant form] results in increased expression of TRP53 protein]; ursodoxicoltaurine inhibits the reaction [APP gene mutant form results in increased expression of TRP53 protein] | PMID:16923170 | | ||||||||||||||||||||||
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