GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | EXP | | 6480464 | CTD | aflatoxin G1 results in increased expression of TNF mRNA; aflatoxin G1 results in increased expression of TNF protein | PMID:25445582 PMID:36997055 | Tnf | multiple interactions | EXP | | 6480464 | CTD | [aflatoxin G1 co-treated with Aflatoxin B1] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; aflatoxin G1 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; TNFRSF1B protein inhibits the reaction [aflatoxin G1 results in increased expression of TNF mRNA]; TNFRSF1B protein inhibits the reaction [aflatoxin G1 results in increased expression of TNF protein] | PMID:22445859 PMID:36997055 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein promotes the reaction [aflatoxin G1 results in increased phosphorylation of H2AX protein]]; TNF protein promotes the reaction [aflatoxin G1 results in increased expression of CYP2E1 protein]; TNF protein promotes the reaction [aflatoxin G1 results in increased phosphorylation of H2AX protein] | PMID:36997055 | | ||||||||||||||||||||||
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