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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733294
Species: Mus musculus
RGD Object: Gene
Symbol: Apaf1
Name: apoptotic peptidase activating factor 1
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apaf1affects expressionEXP 6480464CTDPhenobarbital affects the expression of APAF1 mRNAPMID:23091169
Apaf1increases expressionISOApaf1 (Rattus norvegicus)6480464CTDPhenobarbital results in increased expression of APAF1 mRNAPMID:23273579
Apaf1multiple interactionsISOApaf1 (Rattus norvegicus)6480464CTD[3,4,5,4'-tetramethoxystilbene co-treated with Diethylnitrosamine co-treated with Phenobarbital] affects the expression of APAF1 mRNAPMID:27048571
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