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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731846
Species: Mus musculus
RGD Object: Gene
Symbol: Ces1e
Name: carboxylesterase 1E
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDPhenobarbital results in increased expression of CES1E mRNA

PMID:22513142
multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of CES1E mRNA

PMID:24535843
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.