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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621177
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scd2
Name: stearoyl-Coenzyme A desaturase 2
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scd2increases expressionEXP 6480464CTDPhenobarbital results in increased expression of SCD2 mRNA

PMID:19162173
Scd2affects expressionISORGD:13318676480464CTDPhenobarbital affects the expression of SCD2 mRNA

PMID:19136022, PMID:23091169
Scd2increases expressionISORGD:13318676480464CTDPhenobarbital results in increased expression of SCD2 mRNA

PMID:19482888
Scd2multiple interactionsISORGD:13318676480464CTDNR1I3 protein affects the reaction [Phenobarbital results in increased expression of SCD2 mRNA]

PMID:19482888
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.