Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3214
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ntrk3
Name: neurotrophic receptor tyrosine kinase 3
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ntrk3decreases expressionEXP 6480464CTDPhenobarbital results in decreased expression of NTRK3 mRNAPMID:19162173
Ntrk3multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of NTRK3 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of NTRK3 promoterPMID:25374375
Go Back to source page   Continue to Ontology report