Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gstp1
Name: glutathione S-transferase pi 1
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gstp1increases expressionEXP 6480464CTDPhenobarbital results in increased expression of GSTP1 mRNAPMID:23273579 PMID:2563599
Gstp1multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with Phenobarbital co-treated with Dietary Fats] results in increased expression of GSTP1 protein; [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of GSTP1 proteinPMID:20935162 PMID:36657701
Gstp1decreases expressionISOGSTP1 (Homo sapiens)6480464CTDPhenobarbital results in decreased expression of GSTP1 proteinPMID:28541575
Go Back to source page   Continue to Ontology report