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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1587893
Species: Rattus norvegicus
RGD Object: Gene
Symbol: H1f2
Name: H1.2 linker histone, cluster member
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H1f2increases expressionISOH1f2 (Mus musculus)6480464CTDPhenobarbital results in increased expression of H1F2 mRNAPMID:19482888
H1f2multiple interactionsISOH1f2 (Mus musculus)6480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of H1F2 mRNA; NR1I3 protein affects the reaction [Phenobarbital results in increased expression of H1F2 mRNA]PMID:19482888 PMID:24535843
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