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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320654
Species: Mus musculus
RGD Object: Gene
Symbol: Sult5a1
Name: sulfotransferase family 5A, member 1
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sult5a1affects expressionEXP 6480464CTDPhenobarbital affects the expression of SULT5A1 mRNAPMID:19136022 PMID:23091169
Sult5a1increases expressionEXP 6480464CTDPhenobarbital results in increased expression of SULT1A1 mRNA; Phenobarbital results in increased expression of SULT5A1 mRNAPMID:19270015 PMID:19760798
Sult5a1multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of SULT5A1 mRNAPMID:24535843
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