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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10730
Species: Mus musculus
RGD Object: Gene
Symbol: Hras
Name: Harvey rat sarcoma virus oncogene
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hrasdecreases mutagenesisEXP 6480464CTDPhenobarbital results in decreased mutagenesis of HRAS proteinPMID:11753661
Hrasincreases expressionISOHras (Rattus norvegicus)6480464CTDPhenobarbital results in increased expression of HRAS mRNAPMID:30047161
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