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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552366
Species: Mus musculus
RGD Object: Gene
Symbol: Ntsr1
Name: neurotensin receptor 1
Acc ID: CHEBI:8058
Term: phencyclidine
Definition: A member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects.
Chemical ID: MESH:D010622
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDNTSR1 gene affects the reaction [Phencyclidine results in decreased expression of DRD1 protein]

PMID:20659557
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.