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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3554
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ren
Name: renin
Acc ID: CHEBI:8024
Term: perindopril
Definition: An alpha-amino acid ester that is the ethyl ester of N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvaline
Chemical ID: MESH:D020913
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Renincreases expressionEXP 6480464CTDPerindopril results in increased expression of REN proteinPMID:9383173
Renincreases activityISOREN (Homo sapiens)6480464CTDPerindopril results in increased activity of REN proteinPMID:2549899 PMID:2605800
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