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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621628
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc22a12
Name: solute carrier family 22 member 12
Acc ID: CHEBI:80230
Term: Potassium 2,6-dihydroxytriazinecarboxylate
Definition: An organic molecular entity that has formula C4H2KN3O4.
Chemical ID: MESH:C489337
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a12increases expressionISOSlc22a12 (Mus musculus)6480464CTDpotassium oxonate results in increased expression of SLC22A12 mRNA; potassium oxonate results in increased expression of SLC22A12 proteinPMID:21909718 PMID:22865646 PMID:22967667
Slc22a12multiple interactionsISOSlc22a12 (Mus musculus)6480464CTD4-hydroxystilbene inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; Allopurinol inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 mRNA]; Drugs, Chinese Herbal inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; mulberroside A inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; Plant Extracts inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 mRNA]; Plant Extracts inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; polydatin inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; pterostilbene inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; Quercetin inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 mRNA]; Quercetin inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]PMID:21909718 PMID:22865646 PMID:22967667
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